Joe Biden, the President of the United States, has said Nato “would respond” if Russia uses chemical weapons in Ukraine, BBC reports.
The president – who is in Europe for talks with allies – did not spell out what that might mean.
His comments came on an unprecedented day of emergency summits in Brussels, where Western leaders showed a united front against Russia’s invasion.
Mr Biden is travelling to Poland on Friday where more than two million Ukrainians have fled from the fighting.
Asked whether the use of chemical weapons by Russia’s Vladimir Putin would prompt a military response from Nato, Mr Biden replied that it “would trigger a response in kind”.
“We would respond if he uses it. The nature of the response would depend on the nature of the use,” he said.
Western nations have warned Russia could be preparing to use chemical or biological weapons in Ukraine, as its invasion of the country enters its fifth week.
UK Prime Minister Boris Johnson has said it would be “catastrophic” if Mr Putin used chemical weapons, while Nato Secretary-General Jens Stoltenberg has made it clear it would result in severe consequences.
The White House has set up a national security team to look at how the US and allies should react if Russia launched a chemical attack. But there is no suggestion Nato would respond by using chemical weapons, says BBC US Editor Sarah Smith.
Mr Biden has previously stressed the US and Nato would not send troops to Ukraine over fears of a direct military confrontation with Russia.
The president was speaking after an emergency meeting of Nato leaders to debate how to respond to the possible use of weapons of mass destruction, as well as military aid for Ukraine and tougher sanctions on Moscow.
“The single most important thing is for us to stay united,” the president said after the summit.